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Mesothelioma and Asbestos Exposure Mesothelioma is a result of exposure to asbestos. The exposure could be at work or at the home. Coughing, chest discomfort, and dry throat are all symptoms of asbestosis pleural. Other symptoms include abdominal pain, fluid accumulation and testicular carcinoma. There are four mesothelioma types. Pleural mesothelioma is by far the most common kind. Exposure to Work Asbestos exposure is the leading cause of mesothelioma. This cancer affects the linings of certain organs, like the lungs, or abdomen. This harmful mineral, which is utilized in a variety of industries, can cause fine dust to be inhaled and ingested when it breaks down. Historically, many occupations have had high levels of occupational exposure to asbestos. These include asbestos insulation plumbers, electricians, engineers, shipyard employees and producers of automotive components brake pads, clutches and clutches. Construction workers, who could be exposed to asbestos through their building materials, or when demolition of old buildings, also face a high risk of asbestos exposure. Mesothelioma occurs when mesothelial cells are transformed and begin to grow out of control, creating tumors that spread throughout the body. The majority of mesothelioma cases are in the lungs and the abdomen, but it may develop in other organs like the testicles and the heart. There are many mesothelioma types, and each one is named in honor of the organ tissue it affects. Typically, the signs of mesothelioma manifest 30 to 50 years after the initial exposure. Mesothelioma is a rare cancer that is often difficult to detect and it can take years for the disease to manifest itself. Asbestos sufferers must seek medical attention to receive an diagnosis and treatment. Non-occupational exposure to asbestos may increase the risk of mesothelioma. Indirect or secondary exposure to asbestos occurs when people come in contact with fibers of asbestos through contaminated clothing and household items. These exposures can occur when family members clean a person's clothes or when they reside near an industrial asbestos source. Few population-based case control studies have examined the para-occupational exposure to asbestos and mesothelioma risk. One study found that residents living near an asbestos cement plant in Casale Monferrato (northwest Italy) were at a high risk of mesothelioma. The authors attributed the rise in mesothelioma-related risk to the proximity of residents to the plant, and airborne exposure from the use asbestos cement products on nearby roads and structures. Similar results have been found in other community-based studies that have clearly defined industrial sources for para-occupational exposure. However these studies can be difficult to conduct. Certain studies have struggled to separate out individuals who have been identified as having occupational or para-occupational asbestos exposures, which can lead to error in the assessment of their mesothelioma risk. Environmental Exposure Asbestos is a grouping of minerals that contain microscopic fibers. Asbestos is resistant to chemicals, electricity and fire. It has been used for a variety industrial processes and products. Workers who work with these materials or are exposed in other ways increase their chances of developing mesothelioma. This includes asbestos miners and shipyard workers as well as asbestos-cement producers and insulation. Mesothelioma is also found in hair and clothing of asbestos workers, putting the family at risk. The occupational exposure to asbestos is the main cause mesothelioma. A small number of cases are reported in people who have been exposed to asbestos. In these instances, asbestos fibers may have gotten into the lungs or digestive system through contaminated air, or through eating food that is contaminated. Most often, mesothelioma cases have occurred in the families of asbestos-exposed workers. The diagnosis of mesothelioma usually made decades after asbestos exposure. Tumors are typically found in the chest and abdomen. The most common form of mesothelioma affects the lining of the chest cavity. The second most frequent type of mesothelioma affects the abdominal cavity's lining known as the peritoneum. The mesothelioma cancer cells are classified as epithelioid and sarcomatoid. Epithelioid mesothelioma makes up about 60 70 to 80 percent of all mesothelioma cases, and generally has the highest success rate. Sarcomatoid mesothelioma is more aggressive and has a lower prognosis. Between 10% and 15% of mesothelioma patients have a biphasic type that includes epithelioid and sarcomatoid mesothelioma cells. Mesothelioma is more prevalent in men than women, and the majority of patients diagnosed with mesothelioma were exposed to asbestos via workplace exposure. The exact reason for this gap between men and women is not known. It could be due to more men being employed in fields that typically used asbestos, like manufacturing and construction. A number of studies have demonstrated elevated mesothelioma rates in regions or communities that have multiple asbestos-related industrial sources. For instance, one study of mesothelioma patients in 70 communities around sites that were exposed to contaminated vermiculite at the Libby asbestos mine in Montana found that those who lived within 2000m of the mine were at a higher risk of mesothelioma. Genetic Predisposition In certain cases, genetics may play a role in mesothelioma. The condition is believed to be linked to hereditary mutations in genes that interfere with DNA repair mechanisms. Researchers have identified genes that may make a patient more susceptible to mesothelioma. Some studies have shown that those with a family history of mesothelioma are more likely to develop the disease than those without a family history. The reason for this isn't completely understood. It is known that environmental and occupational asbestos exposure can trigger mesothelioma. However, St. Charles asbestos lawsuit exposed to asbestos develops mesothelioma. Certain mesothelioma patients have not been exposed to asbestos, whereas others who have had extensive occupational exposure never develop this disease. They are more likely to have genetic mutations which interfere with the repair of DNA. A genetic mesothelioma test can be used to determine whether an individual is affected by hereditary gene mutations that can increase the risk of developing the disease. A doctor can conduct the test using a sample of saliva or blood. The sample is sent to a laboratory for testing. The results of the test can typically be found within two weeks. A few families with multiple mesothelioma cases have a mutation in BAP1. This gene is involved in the repair of damaged DNA. The mutation could cause cancerous cells to grow exponentially. cells that then spread to other organs, causing mesothelioma. The genetic mesothelioma test is an effective tool to identify diseases related to asbestos. They can help doctors understand the causes of asbestos-related diseases and develop more efficient treatments. The unintentional exposure to asbestos is preventable by avoiding environmental and occupational exposure to the material. Discuss with your doctor in the event that you have a family background of mesothelioma. Some people can also benefit by participating in mesothelioma testing programs that require a cheek swab or blood sample. In these programs the prognosis of a patient's mesothelioma is evaluated by a team of experts. The patient's mesothelioma treatment program is then designed in accordance with their specific diagnosis. Treatment Mesothelioma is a condition that occurs when asbestos fibers cause damage to the body that can lead to cancer. Asbestos exposure can occur in various ways, including when employees cut down asbestos to remove it, or when people take the fibers home on their clothing and skin after they leave work. The fibers can be absorbed into the lungs and the stomach and cause irritation that can lead to cancer. The signs of mesothelioma could not be evident for as long as 50 years following exposure. Therefore, it is essential that anyone who has been exposed to asbestos should consult their doctor right away. The majority of mesothelioma patients are men, and the most common type of the disease is one that affects the lining of the lungs (pleural mesothelioma). Other types of mesothelioma may occur in the linings the stomach, peritoneum, or the linings of the testicles and heart. As with any form of cancer, mesothelioma can be caused by cells growing uncontrollably, forming a tumour. The abnormal cells can spread to other parts of the body, creating more cancerous tumours. Researchers don't fully understand what causes mesothelioma, but they do know that asbestos exposure is a major risk factor. People who are diagnosed with mesothelioma typically undergo surgery and chemotherapy to alleviate their symptoms and slow the progression of the disease. It's important for people who have been exposed to asbestos to be vigilant about their health and speak with their physicians about their work background. Mesothelioma patients should also be sure to undergo regular tests to check for signs of asbestos exposure and any other possible issues. The most common mesothelioma signs include pain and the buildup of fluid around the lung. Other symptoms include chest pain, feeling that the chest and abdomen are under pressure, abdominal swelling, difficulty in breathing and fatigue, as well a fever. Mesothelioma is a condition that can cause symptoms similar to those of other diseases and conditions. Bloodwork and X-rays can confirm the diagnosis. Some mesothelioma patients might have genetic mutations in their DNA, which increase their chances of developing this disease. These patients should consult their doctor about genetic counseling.